Author links open overlay panelShuNishiguchiMScabPersonEnvelopeMinoruYamadaPhDaYuuKajiwaraMSccTakuyaSonodaMScdKazuyaYoshimuraMSceHirokiKayamaaTakanoriTanigawaaTaikiYukutakeaTomokiAoyamaMD PhDa
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//doi.org/10.1016/j.jcgg.2013.09.002Get rights and content
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Abstract
Background/Purpose
Measures to prevent the development of muscle mass decline should be initiated from midlife. However, the impact of physical activity at midlife on muscle mass in old age remains uncertain. The aim of this cross-sectional study was to determine whether physical activity at midlife influences muscle mass and physical performance in old age.
Methods
A total of 272 Japanese women aged 65 years and older were enrolled in the study. Information about physical activity levels at midlife and in old age were collected using a retrospective questionnaire. We calculated the skeletal muscle mass index in old age and recorded the participants' walking speed and hand grip strength in old age. We then classified the participants into four groups according to their physical activity levels at midlife and in old age and conducted multiple linear regression analysis to determine whether the physical activity levels at midlife and in old age were associated with skeletal muscle mass index and physical performance in old age.
Results
The participants in the groups that were physically inactive at midlife had a significantly lower skeletal muscle mass index in old age than those who were physically active at midlife [p